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Fractional lasers in the intimate area: ablative and non-ablative, what is the difference?

CO2 laser, non-ablative laser, radiofrequency: in intimate medicine the names sound alike, but the technologies do very different things. I try to explain the difference between ablative and non-ablative lasers, what the studies say and what I am evaluating in my practice.

When a patient asks me for «the laser», the first thing I do is ask her which one. That word covers instruments that act at different depths, on different tissues, with different recovery times and risks. Understanding the difference helps you choose, and keeps you from being swayed by a fashionable word.

The common principle: fractional treatment

Almost all lasers used today for skin rejuvenation are fractional. The beam does not treat the whole surface, but divides it into many microscopic columns of heat, separated by healthy tissue. It is precisely that intact surrounding tissue that heals the micro-injuries quickly: an idea first described in 2004 and since then the basis of almost all aesthetic laser technologies.

The heat stimulates fibroblasts, the cells that produce collagen and elastin. The result builds up slowly, over the following weeks and months.

Ablative and non-ablative: the difference

In one sentence: an ablative fractional laser vaporises micro-columns of tissue, opening tiny channels in the skin or mucosa, while a non-ablative fractional laser heats the dermis deep down, leaving the surface intact.

The two families of fractional lasers, in brief.
AblativeNon-ablative
What it doesVaporises micro-columns of tissue, opening tiny channels in the surfaceHeats micro-columns in the dermis, leaving the surface intact
ExamplesCO2 laser, erbium laserLasers with wavelengths absorbed by tissue water, for example between 1,400 and 1,550 nm
RecoveryA few days of redness and small scabsUsually redness and swelling for a few hours or days
SessionsFewer sessions, each more intenseMore sessions, each lighter
In the intimate areaVaginal CO2 laser is the most studied, for dryness and fragility of the mucosa (genitourinary syndrome of menopause)Almost no studies on the external genitalia

The laser I use for the vaginal mucosa is a fractional CO2 laser, so it is ablative: I discuss it on the vaginal CO2 laser page. Radiofrequency microneedling is yet another technology, delivering heat into the dermis through very fine needles: I describe it on its dedicated page.

What the studies say

On the face and body, fractional lasers have been studied for twenty years. In short, ablative lasers achieve more per session but need a few days of recovery; non-ablative lasers are lighter, but more sessions are needed for a comparable result.

Less invasive does not mean risk-free. A review of 34 studies with 1,093 patients (Mirza, 2021) found side effects in 12.2% of patients treated with non-ablative lasers and in 8.3% of those treated with ablative lasers, mostly mild and transient. It is a counter-intuitive finding, and one I remind anyone who asks me for a «light» treatment.

In the intimate area the picture is even less certain. In 2018 the FDA, the US agency that authorises medicines and medical devices, stated that the safety and effectiveness of laser and radiofrequency devices for «vaginal rejuvenation» have not been established. On the skin of the external genitalia, studies with non-ablative lasers are practically non-existent.

What I am evaluating in my practice

For a few months I have been evaluating a 1,470 nm non-ablative fractional laser on the skin of the labia majora and mons pubis. It is a wavelength absorbed mainly by tissue water, which heats the dermis without opening the surface.

I want to be clear on three points:

Until I have solid data I do not consider it an established treatment, and I cannot tell you what results to expect. When the data are there, I will report them here in the same spirit: numbers, limits and risks, without promises.

How to find your way today

Often the answer is a combination. And that is why the consultation comes before any laser.

Frequently asked questions

Is a non-ablative laser safer than an ablative one?

Not necessarily. It does not open the skin and recovery is shorter, but a review of 34 studies with over a thousand patients (Mirza, 2021) found side effects in 12.2% of patients treated with non-ablative lasers and in 8.3% of those treated with ablative lasers. Less invasive does not mean risk-free.

Is vaginal CO2 laser an ablative laser?

Yes. Fractional CO2 laser creates micro-columns of vaporisation in the vaginal mucosa and is used mainly for dryness and fragility after menopause. It is a different treatment from those on the skin of the external genitalia.

How many sessions does a non-ablative laser need?

Generally more than with an ablative laser, because each session is lighter. On the face, several sessions are usually done a few weeks apart; for the intimate area there are no validated protocols yet.

Do you perform non-ablative laser on the external genitalia?

I am evaluating it in a small number of patients, as an off-label use and with systematic data collection. I do not yet consider it an established treatment: at the consultation I also explain the alternatives that have more studies behind them.

Scientific bibliography

  1. Manstein D, Herron GS, Sink RK, Tanner H, Anderson RR – Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury

    Source: Lasers in Surgery and Medicine, 2004 – Wiley

    What it covers: It describes for the first time the idea of treating the skin with many microscopic zones of heat, separated by intact tissue that speeds up healing.

    Why it matters: It is the study from which all fractional lasers, ablative and non-ablative, originate.

  2. Alexiades-Armenakas MR, Dover JS, Arndt KA – The spectrum of laser skin resurfacing: nonablative, fractional, and ablative laser resurfacing

    Source: Journal of the American Academy of Dermatology, 2008 – JAAD

    What it covers: A review of laser technologies for skin rejuvenation, from non-ablative to ablative, with the advantages, limits and recovery times of each.

    Why it matters: It explains well the trade-off between effectiveness per session and recovery time.

  3. Mirza HN, Mirza FN, Khatri KA – Outcomes and adverse effects of ablative vs nonablative lasers for skin resurfacing: a systematic review of 1093 patients

    Source: Dermatologic Therapy, 2021 – Wiley

    What it covers: A review of 34 studies with 1,093 patients: side effects in 9.7% of cases, 12.2% with non-ablative lasers and 8.3% with ablative ones; hypertrophic scars very rare.

    Why it matters: It shows that a less invasive laser is not automatically free of side effects.

  4. U.S. Food and Drug Administration – FDA warns against use of energy-based devices to perform vaginal "rejuvenation" or vaginal cosmetic procedures

    Source: FDA, July 2018 – Medsafe (copy of the warning)

    What it covers: The warning states that the safety and effectiveness of laser and radiofrequency devices for "vaginal rejuvenation" have not been established, reporting burns, scarring and pain.

    Why it matters: It is the context in which any energy-based technology in the intimate area should be read.

Medically reviewed by Dr Giulio Maria Maggi, Plastic Surgeon — last reviewed:

Article written by Dr Giulio Maria Maggi

Dr Giulio Maria Maggi, plastic surgeon in Turin

Aesthetic Plastic Surgeon – Turin, Asti and Alessandria
Medical Director – Aesthetic Clinic (Turin)
Turin Medical Council (Ordine dei Medici di Torino) no. 20595
Member of AICPE – Italian Association of Aesthetic Plastic Surgery

Expertise and areas of interest

Dr Maggi trained internationally, completing advanced training with Prof. José Guerrero Santos (Guadalajara) and with Prof. Andrew A. Jacono (New York) in the Deep Plane facelift technique.

He focuses in particular on:

  • Deep Plane facelift
  • Blepharoplasty
  • Functional and aesthetic intimate surgery
  • Liposculpture and fat grafting (lipofilling)
  • Breast surgery
  • Body contouring

Clinical approach
Combines scientific rigour with natural results, applying advanced protocols focused on morphological well-being.

Signature of Dr Giulio Maria Maggi

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